Four E’s Scientific OptimaFlex Gradient PCR Thermocycler — Single Block (1×96-Well)
The Four E’s Scientific OptimaFlex Single Block Gradient PCR Thermocycler (PCR96GX1) is a versatile and modular PCR platform designed for pharmaceutical, molecular biology, and research laboratories requiring a reliable and upgradeable gradient PCR solution. With a 1×96-well block configuration, a flexible heated lid that automatically adjusts to fit 0.2mL PCR tubes, and a large 10.1-inch LCD touchscreen, the OptimaFlex delivers excellent usability and performance for both routine amplification and gradient optimisation workflows.
The OptimaFlex platform is part of the Four E’s Scientific modular PCR system — designed to accommodate different block configurations including single-block (1×96-well), dual-block (2×48-well), and triple-block (3×32-well) formats. This modular approach provides laboratories with the flexibility to adapt their PCR capacity to changing throughput requirements without replacing the instrument.
Key Features
Flexible Heated Lid
The OptimaFlex features a flexible heated lid that automatically adjusts to fit 0.2mL PCR tubes for optimal sealing — ensuring consistent sample evaporation prevention across all tube formats and eliminating the need for manual lid height adjustment between runs.
Wide Temperature Range
The sample temperature range of 0°C–100°C and heated lid temperature range of 30°C–115°C cover all standard PCR protocols, including denaturation, annealing, and extension steps across a wide variety of target sequences and primer combinations.
10.1-Inch LCD Touchscreen
The large 10.1-inch LCD touchscreen provides a clear and intuitive interface for program entry, real-time run monitoring, and result review — improving usability in busy laboratory environments where multiple users operate the instrument.
Up to 100 Stored Programs
The OptimaFlex supports storage of up to 100 PCR programs, providing ample capacity for laboratories running multiple validated or routine protocols across different targets and applications.
USB Interface for Program Management
The front-panel USB interface enables easy program import and export, and supports device software updates — simplifying protocol management across multiple instruments and laboratory sites.
Modular Block System
The OptimaFlex is compatible with interchangeable block configurations. Spare blocks are available separately, including the 2×48-well dual block and 3×32-well triple block formats — providing upgrade flexibility as laboratory requirements evolve.
Technical Specifications
| Parameter | Specification |
|---|---|
| Model | OptimaFlex Single Block |
| Part Number | PCR96GX1 |
| Sample Capacity | 1×96-well ×0.2mL |
| PCR Reaction Volume | 10–100μL |
| Heated Lid Temperature | 30°C–115°C |
| Sample Temperature Range | 0°C–100°C |
| Heated Lid | Flexible — automatically adjusts to fit 0.2mL PCR tubes |
| Display | 10.1-inch LCD touchscreen |
| Program Storage | Up to 100 programs |
| Connectivity | USB interface (front panel) |
Applications
- Routine PCR amplification — reliable nucleic acid amplification for genotyping, cloning, and diagnostic workflows
- Gradient PCR optimisation — annealing temperature optimisation for new targets and primer combinations
- Pharmaceutical molecular biology — PCR amplification in regulated pharmaceutical research and development environments
- Method development — efficient protocol development and optimisation for new analytical methods
Availability in Ireland
The Four E’s Scientific OptimaFlex Single Block Gradient PCR Thermocycler is available from Varen Scientific — Ireland’s authorised distributor for Four E’s Scientific laboratory instruments, providing local procurement support and documentation assistance for Irish laboratories.
For further information on PCR principles and thermocycler selection, refer to guidance available from Thermo Fisher Scientific’s PCR learning centre.
To request a quote, contact our team or use the Request a Quote button above.











