Four E’s Scientific OptimaFlex Dual-Block Gradient PCR Thermocycler (2×48-Well)
The Four E’s Scientific OptimaFlex Dual Block Gradient PCR Thermocycler (PCR48GX2) is a multi-block PCR platform providing two independent 48-well blocks in a single instrument footprint. Designed for pharmaceutical, molecular biology, and research laboratories requiring simultaneous operation of two independent gradient PCR protocols, the dual-block configuration maximises instrument throughput and flexibility without increasing bench space requirements.
As part of the modular OptimaFlex platform, the PCR48GX2 is compatible with interchangeable block configurations — providing laboratories with the option to adapt their PCR capacity as their throughput and application requirements evolve over time.
Key Features
2×48-Well Dual Block Configuration
Two independent 48-well blocks allow simultaneous operation of two separate PCR protocols, enabling more efficient use of instrument time in high-throughput or multi-project laboratory environments. Each block operates independently, providing full gradient optimisation capability per block.
Flexible Heated Lid
The flexible heated lid automatically adjusts to fit 0.2mL PCR tubes for optimal sealing — ensuring consistent sample integrity and evaporation prevention across all tube formats without manual adjustment between runs.
Wide Temperature Range
Sample temperature range of 0°C–100°C and heated lid temperature range of 30°C–115°C cover all standard PCR protocols across a wide variety of applications and target sequences.
10.1-Inch LCD Touchscreen
The large 10.1-inch LCD touchscreen provides a clear and intuitive interface for program entry and run monitoring — improving usability across multiple users and shifting laboratory environments.
Up to 100 Stored Programs
Supports storage of up to 100 PCR programs, providing capacity for laboratories managing multiple validated or routine protocols across different targets and projects.
Technical Specifications
| Parameter | Specification |
|---|---|
| Model | OptimaFlex Dual Block |
| Part Number | PCR48GX2 |
| Sample Capacity | 2×48-well ×0.2mL |
| PCR Reaction Volume | 10–100μL |
| Heated Lid Temperature | 30°C–115°C |
| Sample Temperature Range | 0°C–100°C |
| Heated Lid | Flexible — automatically adjusts to fit 0.2mL PCR tubes |
| Display | 10.1-inch LCD touchscreen |
| Program Storage | Up to 100 programs |
| Connectivity | USB interface (front panel) |
Applications
- Simultaneous dual-protocol PCR — run two independent PCR protocols concurrently for maximum instrument efficiency
- Gradient PCR optimisation — independent annealing temperature optimisation per block
- High-throughput molecular biology — increased sample capacity for busy laboratory environments
- Pharmaceutical research and development — PCR amplification in regulated environments requiring throughput flexibility
Related Products
Also available in the OptimaFlex modular platform: the Single Block 1×96-Well (PCR96GX1) and the Triple Block 3×32-Well (PCR32GX3).
Availability in Ireland
The Four E’s Scientific OptimaFlex Dual Block Gradient PCR Thermocycler is available from Varen Scientific — Ireland’s authorised distributor for Four E’s Scientific laboratory instruments, providing local procurement support and documentation assistance for Irish laboratories.
For further information on PCR thermocycler selection, refer to guidance from Thermo Fisher Scientific’s PCR learning centre.
To request a quote, contact our team or use the Request a Quote button above.









